Searchable abstracts of presentations at key conferences in endocrinology

ea0031s3.1 | Nurture not nature: epigenetics and disease susceptibility | SFEBES2013

A mouse model of non-genetic inter-generational effects

Rakyan Vardhman

Non-genetic inheritance allows the environmental history of an individual to influence the next generation. This form of inheritance is well documented in worms, fruit-flies and plants. Observational evidence in mammals suggests two forms of non-genetic transgenerational effects; ‘developmental programming’ in response to early life exposures and germ-line transmission of an environmentally induced change i.e. ‘epigenetic inheritance’. However, at present t...